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B. aϡ <4 w/aa : () e w (a: we) / wA()w : CKD-602 <4 e a: ew e q e / iw qġAɥ wqAa A2 bȩ(Taxol) hqA aa 1993e 嬗ei avaa 1994e 刢 i ha 2ee AA ei Ɂ sAᴥ 100a AA aw AaaС bw e ҡi ava. < . aAwA be - e ew qa , a 5ew aw(ew aI 1) - e Aw 124ⴉ, w 1,700ⴥ, wI e 10% w - w wa, a wa w - aA eЁ . be - wqAA e iea aI q e 币 i a - ea ae aAaA e a wa w - i bw i a(wС aeb wa) - qġAɥ(camptothecin) wqAe Aw aw iA e q a taxol qA 2000e wqA b> <4 iw iw 1990eA i, qbAA wqA ⸥ Ai b i e Aw wqA qġAɥ wqAA ge i aA QA aa, () e w (ea: q)Ae ᬉ (w a) a AAei bavaa 2ee sE 100a AA aw aa a bw wqE (CKD-602) eȗaA Aa. 1993eA CKD-602A e s (CKD-602 a qġAɥ iA aa qġAɥi sa eae w)i ŵavaa, ᖡ 97eAe wi e es (a qġAɥA CKD-602i sae w)i iŵaaa wi e wAi ѡava. 1997eA 1998e, 2ee 刁aeia (刢 i a) AA Aaa 1998e 11 KFDA(΁e) w刁a (A678) Bbava. 1999e 2 42,000e 2A a ᬉw (ea: wwa)A A1w wС ŵaA i q, eqA 50%wa aǡ q Aie e Aa wA iсqw A w⸥ wqAbw aС wʼniw bwe ieA gva. ^